JOIN GENTIDE 加入睿联生物

Build the future of AI-driven drug discovery 共建 AI 驱动新药发现 的未来

We are assembling a world-class team of scientists, engineers, and drug developers in Shanghai, Singapore, and San Jose. If you want to work at the frontier of AI and structural biology to build therapies that genuinely matter — we want to hear from you. 我们正在上海、新加坡与圣何塞组建世界级科学家、工程师与新药开发者团队。 如果你希望站在 AI 与结构生物学的最前沿,开发真正有意义的创新药物, 我们期待与你相遇。

View Open Roles 查看开放岗位 Send Your CV 发送简历
Why GenTide 为什么选择睿联

A rare kind of company to work at 一家少见的公司

🧬

Real science, real impact 真实科学,真实影响

Every team member works on programs with a direct path to patients. Our pipeline targets metabolic disease, pain, oncology, and aging — four of the largest unmet needs in medicine. 每位团队成员的工作都与直接到达患者的管线相连。我们的研发管线聚焦 代谢疾病、疼痛、肿瘤与衰老——医学中四大最重要的未满足需求。

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AI-Native from day one 从第一天就 AI-Native

You will work with diffusion models, GNNs, and Cryo-EM structural data in a closed-loop system — not as a side project, but as the core engine of everything we do. 你将在一个真实闭环系统中使用扩散模型、GNN 与冷冻电镜结构数据—— 这不是附属项目,而是我们一切工作的核心引擎。

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Global from the start 生来就是全球化

Offices in Shanghai, Singapore, and San Jose. Dual NMPA + FDA IND filing capability. You will work with and for the global market from day one. 上海、新加坡、圣何塞三地办公。NMPA + FDA 中美双报能力。 从第一天起,你就在为全球市场工作。

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Early-stage, high-ownership 早期阶段,高度参与

We are at the founding stage. Every hire shapes what GenTide becomes. You will have real ownership, real decisions, and real accountability. 我们处于创始阶段。每一位招募的人都在塑造睿联的未来。 你将拥有真实的所有权、真实的决策权与真实的责任感。

Open Positions 开放岗位

Now hiring — Phase 1 core team 现招募 —— 阶段一核心团队

All roles are based in Shanghai unless otherwise noted. Relocation support available. 所有岗位均位于上海,特别注明除外。提供搬迁支持。

🤖 AI & Computational Drug Discovery 🤖 AI 计算药物发现
AI Algorithm Engineer — Molecular Generation AI 算法工程师(结构感知分子生成)
Shanghai上海 Full-time全职 Urgent急招

Core of the DTBL Design loop. You will develop and deploy generative models for structure-aware 3D molecular design, directly powering all four pipeline programs. DTBL Design 环节核心。你将开发并部署结构感知三维分子生成模型,直接驱动四条管线。

Must have必备
  • Diffusion models / Flow Matching (DiffSBDD / SurfGen / PropMolFlow)扩散模型 / Flow Matching(DiffSBDD / SurfGen / PropMolFlow)
  • SE(3)-equivariant GNN architecturesSE(3) 等变 GNN 架构
  • RDKit + PyTorch GeometricRDKit + PyTorch Geometric
  • REINVENT 4 or multi-property SMILES optimizationREINVENT 4 或多性质 SMILES 优化
Nice to have加分项
  • Publication record in AIDD or structural MLAIDD 或结构 ML 相关发表经历
  • Experience with protein-ligand docking (DiffDock)蛋白-配体对接经验(DiffDock)
AI Algorithm Engineer — Activity & ADMET Prediction AI 算法工程师(活性 / ADMET 预测)
Shanghai上海 Full-time全职 Urgent急招

Core of the DTBL Learn loop. You will build and maintain multi-task SAR models and ADMET prediction pipelines that route every generated molecule through a druggability filter before synthesis. DTBL Learn 环节核心。你将构建并维护多任务 SAR 模型与 ADMET 预测管线, 对每个生成分子在合成前完成成药性过滤。

Must have必备
  • Chemprop (message-passing GNN) + ADMET-AI stackChemprop(消息传递 GNN)+ ADMET-AI 技术栈
  • Multi-task SAR modeling多任务 SAR 建模
  • TDC benchmark datasetsTDC 基准数据集使用经验
Nice to have加分项
  • Boltz-2 structure-affinity joint predictionBoltz-2 结构-亲和力联合预测经验
  • Active learning / Bayesian optimization主动学习 / 贝叶斯优化
Scientific Data Engineer 科学数据工程师
Shanghai上海 Full-time全职 Urgent急招

The hidden core of the DTBL loop. You will own dry-wet experiment data standardization, feature engineering, and version management — the data quality layer that determines whether our AI models improve or stagnate. Industry data shows 68% of AI projects fail due to poor data quality; this role exists to ensure GenTide is not one of them. DTBL 闭环的隐性核心。你将负责干湿实验数据标准化入库、特征工程与版本管理—— 这一数据质量层决定我们的 AI 模型是持续进步还是停滞不前。 行业数据显示 68% 的 AI 项目因数据质量差而失败;这个岗位就是为确保睿联不是其中之一。

Must have必备
  • Data pipeline engineering (Python, SQL)数据管道工程(Python, SQL)
  • Scientific data familiarity (assay data, SMILES, bioactivity)科学数据理解(活性数据、SMILES、生物活性)
  • Data versioning tools (DVC, MLflow, or equivalent)数据版本管理工具(DVC、MLflow 或同类)
Nice to have加分项
  • Experience in pharma/biotech lab informatics药企 / 生物技术实验室信息化经验
  • Familiarity with ELN or LIMS systemsELN 或 LIMS 系统使用经验
⚗️ Drug Chemistry ⚗️ 药物化学
Lead Medicinal Chemist 首席药物化学家
Shanghai上海 Full-time全职

One of the most critical scientific roles at GenTide. You will lead lead compound design strategy across all programs, interpret SAR data, and serve as the primary interface between AI-generated candidates and real-world synthesis. GenTide 最关键的科学岗位之一。你将主导各管线先导化合物的设计策略、 解读 SAR 数据,并作为 AI 生成候选物与真实合成之间的核心桥梁。

Must have必备
  • PhD in medicinal chemistry or organic chemistry药物化学或有机化学博士
  • 5+ years lead optimization experience in pharma/biotech5 年以上药企 / 生技公司先导优化经验
  • SAR-driven design across at least one therapeutic area至少一个治疗领域的 SAR 驱动设计经验
Nice to have加分项
  • Experience collaborating with computational chemistry teams与计算化学团队协作经验
  • Peptide or macrocycle chemistry background多肽或大环化学背景
Synthetic Chemist (×2) 合成化学家(×2)
Shanghai上海 Full-time全职

Synthesize AI-designed candidate molecules from mg to g scale. Work closely with medicinal chemistry and the AI team to rapidly iterate on compound series across GLP-1, Nav1.8, and TKI programs. 合成 AI 设计的候选分子(mg 至 g 级)。与药物化学和 AI 团队紧密协作, 快速迭代 GLP-1、Nav1.8 与 TKI 管线化合物系列。

Must have必备
  • MS/PhD in organic or medicinal chemistry有机或药物化学硕士 / 博士
  • Proficiency in multi-step synthesis and purification多步合成与纯化操作熟练
  • NMR, MS, HPLC characterization experienceNMR、MS、HPLC 表征经验
🔬 Structural Biology 🔬 结构生物学
Cryo-EM Scientist 冷冻电镜科学家
Shanghai上海 Full-time全职

One of GenTide's core differentiators. You will own our Cryo-EM pipeline — sample preparation, data collection, and 3D reconstruction — delivering <2.5 Å binding structures that feed directly into AI model retraining. GenTide 核心差异化能力之一。你将主导冷冻电镜全流程——样品制备、数据采集与三维重构—— 输出 <2.5 Å 结合结构,直接反哺 AI 模型迭代。

Must have必备
  • PhD in structural biology, biophysics, or related field结构生物学、生物物理或相关领域博士
  • Hands-on single-particle Cryo-EM experience (<3 Å)单颗粒冷冻电镜实操经验(<3 Å)
  • RELION / cryoSPARC proficiencyRELION / cryoSPARC 熟练使用
Nice to have加分项
  • Drug-target complex structure determination experience药物-靶点复合物结构解析经验
  • Membrane protein structural biology膜蛋白结构生物学背景
🧪 Pharmacology & Biology 🧪 药理学与生物评价
In Vitro Pharmacologist 体外药理学家
Shanghai上海 Full-time全职

Design and execute in vitro assays for all four pipeline programs. Operate HTS dual-cell systems, receptor binding, and functional assays that generate the activity data feeding the DTBL closed loop. 为四条管线设计并执行体外评价实验。操作 HTS 双细胞系、受体结合实验与功能测试, 产出驱动 DTBL 闭环的活性数据。

Must have必备
  • MS/PhD in pharmacology, biochemistry, or related药理学、生物化学或相关领域硕士 / 博士
  • HTRF, FLIPR, or radioligand binding assay experienceHTRF、FLIPR 或放射配体结合实验经验
  • Cell culture and transfection proficiency细胞培养与转染操作熟练
Nice to have加分项
  • GPCR or ion channel assay backgroundGPCR 或离子通道实验背景
  • Experience setting up assays for new targets新靶点实验体系建立经验
🏭 CMC & Process Development 🏭 CMC 与工艺开发
CMC Director CMC 总监
Shanghai上海 Full-time全职 Urgent急招

A critical-path role. IND CMC documentation requires 12–18 months of preparation. You will join from the Lead Optimization stage to review formulation feasibility of AI-designed molecules early — preventing the common "AI design vs. formulation" disconnect that stalls many programs. 关键路径岗位。IND CMC 文件需要 12–18 个月准备周期。你将从先导优化阶段加入, 提前评估 AI 设计分子的配方可行性——防止许多项目在此环节出现的"AI 设计与配方脱节"问题。

Must have必备
  • 10+ years CMC in pharma/biotech10 年以上药企 / 生技 CMC 经验
  • IND CMC filing experience (NMPA and/or FDA)IND CMC 申报经验(NMPA 和 / 或 FDA)
  • Small molecule API and formulation development小分子原料药与制剂开发经验
Nice to have加分项
  • Peptide formulation experience (GLP-1 program benefit)多肽制剂开发经验(GLP-1 管线加分)
  • Dual NMPA + FDA filing experience中美双轨申报经验
🛠️ Operations & Infrastructure 🛠️ 运营与基础设施
Lab Operations Manager 实验室运营管理
Shanghai上海 Full-time全职

Own reagent procurement, instrument maintenance, vendor management, and lab compliance. A well-run lab is a force multiplier for every scientist on the team. 负责试剂采购、仪器维护、供应商管理与实验室合规。 高效运转的实验室是每位科学家效能的倍增器。

Must have必备
  • 3+ years lab operations or management experience3 年以上实验室运营或管理经验
  • Pharma/biotech lab environment familiarity药企 / 生技实验室环境熟悉
  • Vendor negotiation and procurement experience供应商谈判与采购经验

Don't see a perfect fit? 没有完全匹配的岗位?

We are building fast. If you have strong scientific or engineering credentials and care about AI-driven drug discovery, send us your CV — we review all applications. 我们正在快速建设。如果你拥有扎实的科学或工程背景,并对 AI 驱动新药发现充满热情, 请发送简历给我们——我们会认真阅读每一封申请。

Send CV to business@gentide.bio 发送简历至 business@gentide.bio